Dr. Daniel Fung to Give Key Note Address at PDA Global Conference on Pharmaceutical Microbiology

Dr. Daniel Y.C. Fung, Industry Professor, Food and Science, Kansas State University, will deliver this year's key note address at the PDA Global Conference on Pharmaceutical Microbiology. Dr. Fung has more than 30 years experience in rapid and automated microbiology, most notably for the food industry. In his address, Global Developments of Rapid Methods and Automation in Microbiology: A Thirty Year Review and Predictions into the Future, he will discuss improvements in microbial isolation, rapid detection, characterization, and enumeration, as well as industry predictions he had made more than a decade ago.

For a more in-depth look at the PDA meeting and to download the current agenda, please visit the PDA Meeting Overview page.

Could RMMs have prevented E. coli infections in Germany?

I recently posted a news article about an increasing demand for rapid microbiological testing in the food industry (see the post dated May 17 on our News Page). One possible cause for this development is the food manufacturers’ discontent and disappointment over the current quality control methods that are being implemented. Another driving force for this development is the increasing demand for food consumption, as well as the increasing demand to prioritize food safety and regulations.

Now there is an alarming report coming from Germany, where hundreds have taken ill and six have died due to E. coli infections originating from raw vegetables. This recent news highlights the need to employ rapid microbiological methods in the food industry. Here is the news article as provided by CNN World (http:///www.cnn.com).

An E. coli outbreak linked to some raw vegetables has killed at least six people and sickened hundreds in Germany, national and global health authorities said Monday.

The first investigation results released by the German federal unit responsible for disease control and prevention -- the Robert Koch Institute, under Germany's Ministry of Health -- indicated that the most recent infections were likely caused by consuming raw tomatoes, cucumbers and lettuce.

The agency said it is advising consumers to avoid eating those foods, specifically in northern Germany.

The institute is investigating six deaths, according to the World Health Organization. Three of those fatalities, all adults, were caused by hemolytic-uremic syndrome, or HUS, from E. coli. The other three fatalities -- all of them elderly -- were caused by an infection linked to HUS and E. coli, said Dr. Guenael Rodier of the World Health Organization.

The European Centre for Disease Prevention and Control said 329 cases of HUS have been reported since May 2. Though HUS is normally seen in children younger than 5, the vast majority of the current outbreak's cases are adults, and more than two-thirds are women, the center said Monday on its website.

"The source of the outbreak is under investigation, but contaminated food seems the most likely vehicle of infection," it said.

Most of the patients are from, or have been to, northern Germany, primarily Hamburg, Northern Lower Saxony and Mecklenburg-Western Pomerania, it said.

Cases have been reported in Sweden, the United Kingdom, Netherlands and Denmark among people who have visited Germany, most of them northern Germany, it said.

The European Food Safety Alert Network said EHEC, or enterohemorrhagic Escherichia coli, a strain of E. coli that causes hemorrhage in the intestines, was found in organic cucumbers originating from Spain, packaged in Germany, and distributed to countries including Austria, the Czech Republic, Denmark, Germany, Hungary, Luxembourg and Spain.

The Spanish Agency for Food Safety and Nutrition issued a statement saying that two Spanish companies producing cucumbers may be involved in the outbreak, and the agency is awaiting further results from Germany's investigation.

"This is the eye of the storm," said Oliver Grieve, a spokesman for the University Medical Centre Schleswig-Holstein, where one of the deaths occurred. "We're working 24 hours here, and we're getting patients from all over northern Germany including Hamburg."

As of Monday, 115 patients were infected with EHEC -- 68 in the medical center's Kiel campus and 47 in its Lubeck campus. Eighty-two patients were stricken by HUS -- 42 in Kiel and 40 in Lubeck, he said.

The fatality, an 86-year-old woman, died of HUS; her husband remains hospitalized with EHEC, Grieve said.

"Patients are coming in waves," he added.

Cases of bloody diarrhea associated with HUS were first reported in Germany in the second week of May. The detection of E. coli on cucumbers was first reported on May 26.

Germany's Federal Ministry of Food, Agriculture and Consumer Protection advised consumers to cook their food to a minimum temperature of 70 degrees Celsius (about 160 degrees Fahrenheit) for at least two minutes to kill any E. coli bacteria. Freezing food does not kill bacteria reliably, the ministry added.

Russia said Monday it is suspending all imports of vegetables, including tomatoes, cucumbers and salad leaves, produced in Germany and Spain.

The Russian Federal Agency for Health and Consumer Rights, Rospotrebnadzor, said on its website that it has not received information from the European Union on the causes of the infection and the measures taken to "localize and eliminate the outbreak."

"A decision might be taken in the next few hours regarding the ban on imports and sales of vegetables in Russia from all EU countries," the agency said.

New Paper on Rapid Microbial Identification Methods

Jeanne Moldenhauer is writing again, this time on the current trends in microbial identification methods. She provides an overview of some currently available proteotypic identification methods, such as Fourier-Transform (FTIR) spectroscopy, Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) mass spectroscopy, and Raman spectroscopy. To read and download the entire article, please visit American Pharmaceutical Review by clicking on: http://americanpharmaceuticalreview.com/images/article/4_Molden.pdf.